Table 1.
Total N = 2730 | ICS N = 1541 | LABA N = 966 | IP N = 2155 | |
---|---|---|---|---|
Demographic/Behavioral | ||||
Age in years (m, sd) | 66.1 (10.8) | 65.8 (11.3) | 66.0 (10.9) | 66.4 (10.5) |
Male (%) | 97.1 | 97.1 | 97.1 | 97.4 |
Race (%) | ||||
White | 74.9 | 74.7 | 74.7 | 75.4 |
Other | 5.3 | 6.7 | 6.9 | 4.6 |
Unknown | 19.8 | 18.6 | 18.4 | 20.1 |
Smoker within past year (%) | 41.1 | 35.7 | 35.3 | 43.9 |
Missed clinic visits (m, sd) | 0.5 (1.0) | 0.5 (1.1) | 0.6 (1.1) | 0.5 (1.0) |
COPD Severity | ||||
FEV1 in percent-predicted (m, sd) | 43.4 (20.8) | 43.6 (19.9) | 41.2 (19.1) | 41.5 (20.7) |
FEV1 in liters (m, sd) | 1.7 (0.7) | 1.7 (0.7) | 1.6 (0.7) | 1.7 (0.7) |
≥1 inpatient COPD exacerbation (%) | 4.7 | 5.7 | 5.8 | 5.2 |
≥1 outpatient COPD exacerbation (%) | 23.0 | 26.7 | 29.6 | 25.1 |
Frequent exacerbators (%) | 4.3 | 5.6 | 6.6 | 4.7 |
% with clinical COPD diagnosis | 83.1 | 82.1 | 85.2 | 86.9 |
Comorbidities (%) | ||||
Asthma | 23.8 | 33.7 | 32.9 | 17.5 |
Acute Coronary Syndrome | 2.5 | 2.4 | 2.6 | 2.3 |
Congestive Heart Failure | 12.6 | 12.5 | 13.3 | 13.0 |
Depression | 20.6 | 19.6 | 18.3 | 20.6 |
Diabetes | 17.9 | 19.0 | 20.3 | 16.8 |
Edema | 6.2 | 6.2 | 5.6 | 6.4 |
Hypertension | 55.8 | 54.5 | 53.8 | 56.5 |
Lung Cancer | 3.1 | 2.7 | 2.8 | 3.3 |
Neuromuscular disease | 0.3 | 0.3 | 0.2 | 0.3 |
Sleep Apnea | 5.9 | 6.2 | 6.4 | 5.6 |
Schizophrenia | 2.2 | 2.3 | 1.9 | 2.3 |
Medication classes (m, sd) | 11.9 (6.4) | 12.6 (6.5) | 12.7 (6.5) | 12.2 (6.5) |
Medication adherence | ||||
% adherent to ICS | – | 19.8 | – | – |
% adherent to LABA | – | – | 30.6 | – |
% adherent to IP | – | – | – | 25.6 |
*m = mean; sd = standard deviation