Table 3.
Odds of Medication Adherence Based on Baseline Adherence to Different Classes of Medication
| Baseline Adherence (categorized by ReComp score) | Odds of ICS Adherence (95 % CI) | Odds of LABA Adherence (95 % CI) | Odds of IP Adherence (95 % CI) | |
|---|---|---|---|---|
| Inhaled corticosteroid | Poor (0 to <0.20) | 1.00 | 1.00 | 1.00 |
| Moderate (≥0.20 to <0.80) | 0.85 (0.66–1.10) | 0.98 (0.67–1.41) | 0.88 (0.66–1.18) | |
| Good (≥0.80 to <1.0) | 2.87 (1.96–4.20) | 1.87 (1.09–3.23) | 1.21 (0.77–1.90) | |
| Excellent (1.0) | 4.79 (3.22–7.12) | 3.30 (1.89–5.74) | 1.88 (1.21–2.92) | |
| Long-acting beta-agonist | Poor | 1.00 | 1.00 | 1.00 |
| Moderate | 0.88 (0.60–1.29) | 1.08 (0.79–1.49) | 0.83 (0.56–1.22) | |
| Good | 1.84 (1.17–2.90) | 3.61 (2.39–5.47) | 1.06 (0.67–1.68) | |
| Excellent | 1.71 (1.03–2.84) | 6.60 (3.92–11.11) | 1.43 (0.86–2.38) | |
| Ipratropium bromide | Poor | 1.00 | 1.00 | 1.00 |
| Moderate | 0.85 (0.61–1.19) | 1.49 (0.98–2.27) | 1.38 (1.10–1.73) | |
| Good | 2.30 (1.46–3.61) | 2.24 (1.27–3.94) | 2.52 (1.81–3.50) | |
| Excellent | 1.41 (0.94–2.10) | 1.82 (1.11–3.00) | 14.13 (10.00–19.97) | |
*Reference group for each model is poor baseline adherence (ReComp score <0.20)
†All models were adjusted for age, gender, race, missed clinic visits, FEV1, occurrence of ≥1 outpatient COPD exacerbations, asthma, lung cancer, and number of medication classes