Table I.

Composition of the Fasted- and Fed-State Simulated Intestinal Fluids Proposed for Biorelevant Dissolution Testing (FaSSIF-V2 and FeSSIF-V2)

Composition/property	FaSSIF-V2	FeSSIF-V2
Sodium taurocholate (mM)	3	10
Lecithin (mM)	0.2	2
Maleic acid (mM)	19.12	55.02
Sodium chloride (mM)	68.62	125.5
Sodium hydroxide	34.8	81.65
Glyceryl monooleate (mM)	–	5
Sodium oleate	–	0.8
Osmolality (mOsm kg−1)	180 ± 10	390 ± 10
Buffer capacity (mmol l−1∆pH)	10	25
pH	6.5	5.8

Adapted from Jantratid et al. (49)