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. 2012 Oct 3;32(40):13701–13708. doi: 10.1523/JNEUROSCI.2107-12.2012

Figure 6.

Figure 6.

Activating dephosphorylation of GSK3β and inactivating dephosphorylation of Akt in hippocampal slices of APP/PS1 mice is reversed by GLP-1(9-36)amide. A, In slices from wild-type (WT) mice, GLP-1(9-36)amide treatment did not change phosphorylated GSK3β levels on serine 9 (p-GSK3β). n = 6. B, Reduced level of phospho-GSK3β in APP/PS1 mice was reversed by GLP-1(9-36)amide. n = 6. C, In slices from wild-type mice, GLP-1(9-36) treatment did not change phosphorylated Akt levels on serine 473 (p-Akt). n = 6. D, Reduced levels of phospho-Akt in APP/PS1 mice was reversed by GLP-1(9-36)amide. n = 6. veh, Vehicle.