Fig. 1.

Protein network constructed using sub-networks that are altered by waterborne exposure to 17β-trenbolone in livers of the fathead minnow liver. Abbreviations are as follows: ABP1, amiloride binding protein 1 (amine oxidase [copper-containing]); ACADL, acyl-CoA dehydrogenase, long chain; ACADM, acyl-CoA dehydrogenase, C-4 to C-12 straight chain; AHCY, adenosylhomocysteinase; ALDH1A1, aldehyde dehydrogenase 1 family, member A1; ANPEP, alanyl (membrane) aminopeptidase; CAT, catalase; CELA1, chymotrypsin-like elastase family, member 1; CYCS, cytochrome c, somatic; EEF2, eukaryotic translation elongation factor 2; FABP1, fatty acid binding protein 1, liver; FABP2, fatty acid binding protein 2, intestinal; FABP3, fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); FKBP1A, FK506 binding protein 1A, 12kDa; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSTA1, glutathione S-transferase alpha 1; GSTA5, glutathione S-transferase alpha 5; HIST1H1C, histone cluster 1, H1c; HMGB3, high mobility group box 3; HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10; HSPA8, heat shock 70kDa protein 8; HSPD1, heat shock 60kDa protein 1 (chaperonin); MAT1A, methionine adenosyltransferase I, alpha; MIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor); MYH11, myosin, heavy chain 11, smooth muscle; P4HB, prolyl 4-hydroxylase, beta polypeptide; PPIA, peptidylprolyl isomerase A (cyclophilin A); PPIB, peptidylprolyl isomerase B (cyclophilin B); PRDX1, peroxiredoxin 1; PRDX2, peroxiredoxin 2; RGN, regucalcin (senescence marker protein-30); SCP2, sterol carrier protein 2; SET, SET nuclear oncogene; SOD1, superoxide dismutase 1, soluble; SOD2, superoxide dismutase 2, mitochondrial; SPTAN1, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin); TKT, transketolase; TPT1, tumor protein, translationally-controlled 1; TXN, thioredoxin; YBX1, Y box binding protein 1.