Table 6.

Relationship between pH and the Regeneration by Hydroxylamine of [³H]CPX Binding Following Inhibition by Compound 20

pH	reversal of inhibition (% control)
6.0	6
6.5	8
7.4	14 ± 3
8.5	13 ±1
9.5	15 ±3
10.5	9±3

^aData are means ± s.e.m. of three experiments or the mean for two experiments. After incubation with the isothiocyante derivative 20 at 37 °C for 1 h, membranes were washed three times, incubated with hydroxylamine (300 mM) for 1 h at 37 °C, washed three times, and then incubated with 0.2 nM [³H]CPX (14).