Superposition of RovA and SlyA from S. enterica serovar Typhimurium. Shown is a schematic representation of a RovA dimer in complex with DNA. The SlyA dimer is shown in green, the RovA dimer in blue, and the DNA in orange (phosphate sugar backbone) and purple (base pairs). The flexible loop between helices α5 and α6 is enlarged in the inset. Gly-116, which is important for thermosensing, and Ala-116, the equivalent amino acid of Salmonella SlyA, are illustrated.