FIGURE 6.
T cells from mice treated with p28 or p28/p40 were less efficient in transferring EAU to naïve syngeneic mice. A, LN cells from pMIB-, p28-, or p28/p40-treated EAU mice (day 21 after immunization) were restimulated for 3 days in medium containing IRBP, and proliferation was assessed by the [3H]thymidine incorporation assay. B, IRBP-stimulated T cells from pMIB-, p28-, or p28/P40-treated EAU mice were transferred (1 × 107 cells/mouse) into naïve syngeneic C57BL/6 recipient mice. Ten days after adoptive transfer, fundoscopy was performed on the enucleated eyes.