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Effects of CTD truncation on macroscopic desensitization kinetics
The values represent the means ± S.E. for each data set.
| Condition | τD | Iss | Iss/Ipk | n |
|---|---|---|---|---|
| ms | pa | |||
| N1/2A | 1000 ± 100 | 440 ± 60 | 0.67 ± 0.03 | 8 |
| N1Δ/2A | 700 ± 100 | 600 ± 200 | 0.49 ± 0.05a | 10 |
| N1/2AΔ | 630 ± 50a | 210 ± 50a | 0.29 ± 0.02a | 9 |
| N1Δ/2AΔ | 370 ± 20a | 320 ± 40a | 0.23 ± 0.01a | 10 |
a Significant decrease relative to the full length receptor (p < 0.05).
