Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Knockdown of HEXIM1 releases the cell cycle arrest induced by p53. HCT116 cells were transiently transfected with the indicated expression (i.e. p53 or an empty vector, pcDNA6) and shRNA (shControl or shHEXIM1) plasmids. The transfected GFP+ cells were gated and analyzed for cell cycle status by FACS as described under “Experimental Procedures.” Similar observations were obtained in at least two independent experiments.
