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. 2012 Aug 31;287(43):36536–36543. doi: 10.1074/jbc.M112.398396

TABLE 2.

Main amino acids in contact with the water channel

Listed are amino acids close to the water channel as mapped in Fig 2A. The c-protomer with the deprotonated Glu61 is denoted n. During ATP synthesis, the protomers to the left (in the orientation of Fig. 1A) are the next to be rotated into proton release position and are thus numbered n−1 and n−2. Accordingly, the protomer to the right is denoted n+1.

Protomer Amino acid
n−2 Glu46
n−1 Glu46, Gly47, Arg50, Gly51, Leu54
n Glu46, Gly47, Lys48, Arg50, Gly51, Leu55, Ala58, Phe59, Met60, Glu61, Ile65
n+1 Tyr66