Table 1.

S. cerevisiae strains used in this work

Strains	Relevant genotype	Source
CEN.PK2-1C	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2	EUROSCARF, Frankfurt
Isoy8	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δilv2::loxP	This work
Isoy10	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δilv3::loxP	This work
Isoy12	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δilv5::loxP	This work
Isoy16	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δilv2::loxP Δilv5::loxP Δilv3::loxP	This work
Isoy17	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δilv2::loxP Δilv5::loxP Δilv3::loxP; unknown beneficial mutations for growth on media lacking valine	This work
Isoy21	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δpdc1::loxP Δpdc5::loxP Δpdc6::loxP; unknown beneficial mutations for growth on media with glucose as sole carbon source	This work
JDY4	MATa leu2-3,112 ura3-52 trp1-289 his3-_1 MAL2-8c SUC2 Δadh1::loxP Δadh3::loxP Δadh5::loxP-kanMX-loxP	Boles, lab stock