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Effects of DKP derivatives (10 μM, structures in Scheme 2) on concentration–response curves for intracellular Ca2+ changes induced by 2-MeSADP acting at P2Y1 receptors expressed in 1321N1 astrocytoma cells. The cells were pre-treated for 20 min at room temperature with antagonist before application of the agonist 2-MeSADP.
