Table 4.

Univariate analysis in the validation cohort

Factor	5-y FFS, %	P	5-y OS, %	P
Age (≥ 45 y)
No	74	.49	91	< .01
Yes	69		77
Sex
Female	77	.39	90	.95
Male	70		88
Stage 4 disease
No	77	.01	91	.12
Yes	57		84
Albumin (< 4 g/dL)
No	74	.96	87	.9
Yes	73		89
Hemoglobin (< 10.5 g/dL)
No	77	.17	91	.08
Yes	58		76
WBC count (≥ 15 000/mm3)
No	73	.85	89	.67
Yes	76		86
Lymphocyte count (< 600/mm3 or < 8%)
No	77	.02	89	.48
Yes	25		78
IPS (≥ 3)
No	74	.65	91	.34
Yes	70		86
CD68
≤ 12.7% (CD68low)	78	.04	94	< .01
> 12.7% (CD68high)	64		81
CD163
≤ 16.8% (CD163low)	82	< .01	96	< .01
> 16.8% (CD163high)	63		81
EBER
Negative	75	.24	90	.43
Positive	62		83