Table 4.
Gene symbol (HGNC) | Gene symbol (IUPHAR) | Human | Mice | |||||
---|---|---|---|---|---|---|---|---|
Chemosensory function | A | B | C | D | E | C57BL/6J | DBA/2J | |
HMOX2 (HO-2) | p | p | p | p | p | p | p | |
NOX1 | a | a | a | a | a | a | a | |
CYBB (NOX2) | p | p | p | p | p | a | p | |
NOX3 | a | a | a | a | a | a | a | |
NOX4 | p | p | p | p | p | p | p | |
NOX5 | a | a | a | a | a | a | a | |
DUOX1 | a | a | a | a | a | a | a | |
DUOX2 | a | a | a | a | a | a | a | |
SOD2 | p | p | p | p | p | p | p | |
CAT | p | p | p | p | p | p | p | |
CTH (CSE) | p | p | p | p | p | a | a | |
CBS | u | u | u | u | u | p | a | |
PRKAA1 (AMPK) | p | p | p | p | p | u | p | |
HIF1A | p | p | p | p | p | p | p | |
EPAS1 | p | p | p | u | u | a | a | |
NOS1 | u | u | u | u | u | a | p | |
K+ channels | ||||||||
KCNA1 | Kv1.1 | a | a | a | a | a | a | p |
KCNA2 | Kv1.2 | u | u | u | u | u | a | a |
KCNA3 | Kv1.3 | a | a | a | a | a | a | a |
KCNA5 | Kv1.5 | p | p | a | p | p | p | p |
KCNB1 | Kv2.1 | p | p | p | p | p | p | p |
KCNC1 | Kv3.1 | a | a | a | a | a | a | a |
KCNC2 | Kv3.2 | a | a | a | a | a | u | a |
KCNC3 | Kv3.3 | a | a | a | a | a | a | p |
KCND1 | Kv4.1 | a | a | p | a | a | p | p |
KCND2 | Kv4.2 | a | a | a | p | p | a | p |
KCND3 | Kv4.3 | a | a | a | a | a | a | p |
KCNK2 | TREK-1 | a | a | a | a | a | a | p |
KCNK3 | TASK-1 | p | p | p | p | p | a | p |
KCNK9 | TASK-3 | a | a | a | a | a | nd | nd |
KCNK13 | THIK-1 | a | a | a | a | a | a | a |
KCNK15 | TASK-5 | a | a | a | a | a | a | a |
KCNMA1 | KCa1.1 | p | p | p | p | p | p | p |
(Maxi-K, BKCa, slo) |
Abbreviations: p, present call; a, absent; u, uncertain (due to the conflicting results from the multiple probe sets interrogating the same gene), nd, not detected. Expression calls for HO-2, Maxi-K and TASK-1 were shown also in our previous publication (Fagerlund et al. 2010). KCNK9 (TASK-3) gene was not included in the set of oligonucleotides present on Affymetrix mouse arrays and therefore the expression could not be detected. HGNC, Human Genome Name Classification), IUPHAR, International Union of Pharmacology. In parentheses, frequently used gene symbol synonyms. Full gene names are presented in the Supplementary Table S13.