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. 2012 Jun 6;590(Pt 16):3953–3964. doi: 10.1113/jphysiol.2012.235820

Figure 5. P/Q-type calcium channel blocker on the effect of XE991 on mEPSC frequency.

Figure 5

A and B, representative mEPSC recordings obtained from a CA1 pyramidal neuron in which the blocking of P/Q-type of calcium channels by 200 nmω-agatoxin TK did (A) or did not (B) prevent the effect of 10 μm XE991. The left panels include data from recordings in the presence of ω-agatoxin TK before the application of XE991, and the right panels include data from recordings after the application of XE991. C and D, cumulative probability plots of mEPSC frequency obtained by pooling data from CA1 pyramidal neurons before (continuous lines) and after (dashed lines) the application of XE991 in the presence of ω-agatoxin TK that did (C) or did not (D) prevent the effect of XE991.