Table 2.

Effects of MK801 on electrophysiological changes induced by sevoflurane preconditioning

Groups	Amplitude of initial hyperpolarization	Latency of rapid depolarization	Membrane potential at 10 min hypoxia	Recovery (%)	n
Untreated	2.4 ± 0.15	288 ± 7	−0.3 ± 0.2	0	6
Sevoflurane, 4%	4.2 ± 0.25*	516 ± 15*	−52 ± 9*	83	6
MK801, 25 μm+ sevo, 4%	3.4 ± 0.15*	438 ± 39*	−30 ± 13*	50	6
MK801, 100 μm+ sevo, 4%	3.5 ± 0.20*	481 ± 29*	−48 ± 12*	75	4
MK801, 25 μm	2.8 ± 0.14	351 ± 21	−0.8 ± 0.5	0	4
MK801, 100 μm	2.9 ± 0.15	408 ± 180*	−15 ± 2	0	2

^*P < 0.01 compared with untreated group.