Table 1. Distribution of diagnostic phenotype in the combined sample in each of the subtypes identified by the latent class analysis.
| Number of subjects per diagnostic phenotype (proportion) | |||||||
|---|---|---|---|---|---|---|---|
| BP | SZ | SZ | No | ||||
| Broad | Broad | Affective | Diagnosis | ||||
| Dimension | Subtype | Signal | n=202 | n=135 | n=38 | n=80 | Total n=455a |
| Mania | 1 | 34 (0.26) | 43 (0.33) | 1 (0.01) | 52 (0.40) | 130 (1) | |
| 2 | 13q14 | 168 (0.52) | 91 (0.28) | 37 (0.11) | 27 (0.08) | 323 (1) | |
| Delusion | 1 | 52 (0.55) | 2 (0.02) | 0 (0) | 40 (0.43) | 94 (1) | |
| 2 | 2q34 | 112 (0.59) | 37 (0.19) | 13 (0.07) | 29 (0.15) | 191 (1) | |
| 3 | 9q33 | 38 (0.23) | 94 (0.56) | 25 (0.15) | 10 (0.06) | 167 (1) | |
| Hallucination | 1 | 88 (0.59) | 6 (0.04) | 0 (0) | 55 (0.37) | 149 (1) | |
| 2 | 113 (0.38) | 124 (0.41) | 38 (0.13) | 24 (0.08) | 299 (1) | ||
| Depression | 1 | 12 (0.17) | 42 (0.60) | 3 (0.04) | 13 (0.19) | 70 (1) | |
| 2 | 190 (0.49) | 93 (0.24) | 35 (0.09) | 66 (0.17) | 384 (1) | ||
| Bizarre behavior | 1 | 63 (0.43) | 18 (0.12) | 3 (0.02) | 61 (0.42) | 145 (1) | |
| 2 | 15q25 | 139 (0.45) | 117 (0.38) | 35 (0.11) | 18 (0.06) | 309 (1) | |
| Affective blunting | 1 | 98 (0.59) | 6 (0.04) | 4 (0.02) | 58 (0.35) | 166 (1) | |
| 2 | 103 (0.36) | 128 (0.45) | 34 (0.12) | 21 (0.07) | 286 (1) | ||
| Thought disorder | 1 | 56 (0.41) | 18 (0.13) | 3 (0.02) | 60 (0.44) | 137 (1) | |
| 2 | 146 (0.46) | 116 (0.37) | 35 (0.11) | 19 (0.06) | 316 (1) | ||
| Alogia | 1 | 111 (0.57) | 20 (0.10) | 5 (0.03) | 58 (0.30) | 194 (1) | |
| 2 | 89 (0.35) | 112 (0.44) | 33 (0.13) | 19 (0.08) | 253 (1) | ||
| Anhedonia | 1 | 44 (0.59) | 4 (0.05) | 1 (0.01) | 26 (0.35) | 75 (1) | |
| 2 | 116 (0.52) | 44 (0.20) | 23 (0.10) | 40 (0.18) | 223 (1) | ||
| 3 | 7p14 | 41 (0.26) | 87 (0.56) | 14 (0.09) | 13 (0.08) | 155 (1) | |
| Apathy | 1 | 40 (0.53) | 4 (0.05) | 3 (0.04) | 28 (0.37) | 75 (1) | |
| 2 | 161 (0.43) | 131 (0.35) | 35 (0.09) | 51 (0.13) | 378 (1) | ||
Abbreviations: BP, bipolar disorder; SZ, schizophrenia.
a
Some subjects had missing values for some of the dimensions. Therefore, the total number of subjects may slightly vary from one dimension to another (from 447 to 455).