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. Author manuscript; available in PMC: 2013 Sep 11.
Published in final edited form as: Biochemistry. 2012 Aug 29;51(36):7078–7086. doi: 10.1021/bi2016712

Table 2.

Binding and Antiviral Activities of DV1 and DV1 Dimera

Analog
Designation		 CXCR4 Binding
(nM)		 Antiviral Activity
Using Infectious
Virus Assays (μM)		 Antiviral Activity
Using Single-Cycle
Focal Infectivity
Assays (μM)
DV1 43 ±5.01 12.1 ±3.26 24 ±0.00
DV1 Dimer 3.0 ± 0.52 4.4 ±3.10 10 ±0.49
a

The binding and antiviral activities of DV1 and DV1 dimer are shown by their IC50 values.