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Activated p38 and Akt signaling pathways are blocked by the treatment with p38 and Akt inhibitors when administered singly or in combination. (A) Immunofluorescence staining showing expression of phosphorylated p38, mTOR and Akt. (B) Western blot analysis showing effects of single and combined treatments with p38 and Akt inhibitors on the expression of total and phosphorylated p38, Akt and MAPKAP-2.
