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. 2012 Oct 13;35(11):2377–2383. doi: 10.2337/dc12-0701

Figure 3.

Figure 3

Correlations of compensatory insulin secretion and pancreatic TG levels, expressed as fat-to-water ratio (f/w %), across race/ethnic groups. The direct relationship between compensatory insulin secretion and pancreatic TG levels is specific to race/ethnicity. Black subjects (left), who have low levels of pancreatic TGs, have a robust compensatory insulin secretion that was predicted exclusively by pTG levels: AIRg = 266 + 247 × pancreatic TGs. White subjects (middle), with higher levels of pancreatic steatosis, have suppressed compensatory insulin secretion compared with black subjects, but it still was predicted exclusively by pancreatic TG levels: AIRg = 183 + 27 × pancreatic TGs. In Hispanic subjects (right), compensatory insulin secretion is entirely suppressed, and its direct relationship to pancreatic TGs is negative. In Hispanics, compensatory insulin secretion was predicted by a combination of visceral fat mass, pancreatic TGs, and hepatic TGs with negative contribution from pancreatic TG levels: AIRg = 207 + 2 × visceral fat mass – 38 × pancreatic TG + 17 × hepatic TGs.