Table 2.
The pooled estimates of different imaging modalities in cN0 neck evaluation
| Modalities |
Sensitivity (95%CI) |
Specificity (95%CI) |
LR + (95%CI) |
LR- (95%CI) |
QUADAS score* (95%CI) |
|---|---|---|---|---|---|
|
CT |
0.52 (0.39 ~ 0.65) |
0.93 (0.87 ~ 0.97) |
7.9 (3.6 ~ 17.4) |
0.51 (0.38 ~ 0.68) |
8.1 (3.8 ~ 12.4) |
|
MRI |
0.65 (0.34 ~ 0.87) |
0.81 (0.64 ~ 0.91) |
3.4 (1.8 ~ 6.2) |
0.44 (0.21 ~ 0.93) |
7.6 (4.1 ~ 11.1) |
|
PET |
0.66 (0.47 ~ 0.80) |
0.87 (0.77 ~ 0.93) |
5.2 (2.6 ~ 10.4) |
0.39 (0.24 ~ 0.65) |
10 (6.9 ~ 13.1) |
| US | 0.66 (0.54 ~ 0.77) | 0.78 (0.71 ~ 0.83) | 3.0 (2.1 ~ 4.2) | 0.44 (0.3 ~ 0.64) | 7.5 (3.6 ~ 11.4) |
*Yes: 1; No/unclear: 0.
LR+: likelihood ratio positive; LR-: likelihood ratio negative.