Table 1.
Functional group | Drug | SLN formulation | Physical mixture | Tristearin | Phospholipon 80 H |
---|---|---|---|---|---|
N-H stretch |
3464 cm-1 |
3444.8 cm-1 |
3464.15 cm-1 |
Absent |
Absent |
C = 0 stretch |
1677 cm-1 |
1635.64 cm-1 |
1678.07 cm-1 |
Absent |
Absent |
Aromatic C-H stretch |
3080.75 cm-1 |
Absent |
2954.95 cm-1 |
2954.95 cm-1 |
2954.95 cm-1 |
C = C stretch |
1605 cm-1 |
1635.64,1558.48 cm-1 |
1604.77 cm-1 |
Absent |
Absent |
C≡N |
1384.89 cm-1 |
1373.32 cm-1 |
1384.89 cm-1 |
Absent |
Absent |
CHO aldehydic group |
Absent |
1732.80 cm-1 |
1735.93 cm-1 |
1728.22 cm-1 |
1725.92 cm-1 |
Methylene C-H asym stretch |
Absent |
Absent |
2916.37 cm-1 |
2914.44 cm-1 |
2916.37 cm-1 |
Polymeric |
Absent |
3444.87 cm-1 |
3280.92 cm-1 |
Absent |
3398.57 cm-1 |
|
|
|
|
|
3377.26 cm-1 |
O-H stretch | 3419.97 cm-1 | 3281.93 cm-1 |