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. 2012 Jun 13;11:72. doi: 10.1186/1476-511X-11-72

Table 1.

FTIR interpretation of CBZ SLN comparative to pure drug physical mixture and polymers

Functional group Drug SLN formulation Physical mixture Tristearin Phospholipon 80 H
N-H stretch
3464 cm-1
3444.8 cm-1
3464.15 cm-1
Absent
Absent
C = 0 stretch
1677 cm-1
1635.64 cm-1
1678.07 cm-1
Absent
Absent
Aromatic C-H stretch
3080.75 cm-1
Absent
2954.95 cm-1
2954.95 cm-1
2954.95 cm-1
C = C stretch
1605 cm-1
1635.64,1558.48 cm-1
1604.77 cm-1
Absent
Absent
C≡N
1384.89 cm-1
1373.32 cm-1
1384.89 cm-1
Absent
Absent
CHO aldehydic group
Absent
1732.80 cm-1
1735.93 cm-1
1728.22 cm-1
1725.92 cm-1
Methylene C-H asym stretch
Absent
Absent
2916.37 cm-1
2914.44 cm-1
2916.37 cm-1
Polymeric
Absent
3444.87 cm-1
3280.92 cm-1
Absent
3398.57 cm-1
 
 
 
 
 
3377.26 cm-1
O-H stretch   3419.97 cm-1     3281.93 cm-1