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Disposition of a) paclitaxel, Phe272 and His229, and b) paclitaxel, Lys19 and Glu22 in paclitaxel-bound β-tubulin (pdb ID: 1JFF). Although Lys19 is far from paclitaxel, its role in intra-helix interaction is emphasized by its proximity to Glu22.
