Figure 4.

Color photographs and logarithmically scaled fluorescent images of LS174t tumor cell line from a typical orthotopic mouse model treated with PNA-conjugated NIR fluorescent HSA nanoparticles. 6 mice were anesthetized and treated with a 0.1% particle dispersion in PBS, via the anus. 20 min later the colons were extensively washed with PBS and were then allowed to recover for 1.5 h (A) and for 4 h (B). The colons were then removed and treated as described in the experimental part.