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Man-LAM and PGL-1 inhibit TCR- and TCR/CD28-induced T-cell proliferation. Bar diagram showing mean ± SEM of tritiated thymidine (3 H) uptake by PBMCs of healthy individuals (N = 5) after stimulation with α-CD3 or α-CD3 + α-CD28 in presence or absence of Man-LAM and PGL-1 at the end of 72 hrs. Experiments were performed in triplicates.
