Table 3. Univariate analysis of the impact of HLA Class I alleles on CD4+ T cell count in 2031 HIV-1 C-clade infected Southern African subjects (q<0.2).
| HLA allelea | Phenotypic frequency (%) | Weightb | p-value | q-value |
| B*40 | 0.5 | 0.28 | 3.55E-02 | 0.11 |
| B*57 | 6.2 | 0.23 | 1.21E-08 | 7.96E-07 |
| A*33 | 4.8 | 0.15 | 8.70E-04 | 6.38E-03 |
| B*14 | 7.1 | 0.13 | 2.89E-04 | 3.28E-03 |
| Cw*12 | 3.2 | 0.12 | 2.81E-02 | 9.28E-02 |
| A*74 | 10.2 | 0.11 | 4.87E-04 | 4.60E-03 |
| B*81 | 10.0 | 0.11 | 6.91E-04 | 5.70E-03 |
| B*58:01 | 10.6 | 0.10 | 1.38E-03 | 7.60E-03 |
| Cw*18 | 11.6 | 0.10 | 1.14E-03 | 7.49E-03 |
| B*35 | 4.1 | 0.09 | 6.65E-02 | 0.19 |
| Cw*04 | 23.6 | 0.09 | 6.04E-05 | 1.33E-03 |
| Cw*08 | 10.9 | 0.08 | 1.04E-02 | 3.84E-02 |
| B*44 | 16.6 | 0.07 | 4.93E-03 | 2.17E-02 |
| A*30 | 36.3 | -0.05 | 1.57E-02 | 5.44E-02 |
| A*23 | 18.7 | -0.05 | 4.44E-02 | 0.13 |
| A*68:01 | 6.4 | -0.07 | 7.04E-02 | 0.19 |
| Cw*06 | 29.4 | -0.08 | 1.70E-04 | 2.81E-03 |
| A*66 | 8.3 | -0.09 | 7.74E-03 | 3.01E-02 |
| B*45 | 9.6 | -0.10 | 4.00E-03 | 1.88E-02 |
| B*08 | 10.6 | -0.10 | 1.33E-03 | 7.59E-03 |
| B*18 | 6.1 | -0.11 | 5.59E-03 | 2.31E-02 |
| Cw*16 | 11.7 | -0.11 | 2.99E-04 | 3.28E-03 |
| B*58:02 | 22.0 | -0.12 | 9.20E-08 | 3.04E-06 |
| B*41 | 1.9 | -0.22 | 2.05E-03 | 1.04E-02 |
a
Alleles in bold and underlined are those that remain significant with a more stringent FDR of q<0.05.
b
Alleles with a positive weight (above double line) are associated with statistically significant disease control; alleles with a negative weight (below double line) are associated with hazardous (detrimental) outcome.