Table 4. List of 12 potential biomarker genes.
Genes | Entrez Gene ID | Fold upregulation inbrain | Fold upregulation inliver |
Lyz1: lysozyme 1 | 17110 | 12.2 | 6.4 |
Lyz2: lysozyme 2 | 17105 | 9.62 | 6.91 |
C1qb: complement component 1q, beta polypeptide | 12260 | 3.7 | 2.2 |
Lgals3: Lectin, galactose binding, soluble3 | 16854 | 3.38 | 36.39 |
C1qa: complement component 1q, alpha polypeptide | 12259 | 2.72 | 1.61 |
Grn: granulin | 14824 | 2.26 | 1.58 |
Ctss: cathepsin S | 13040 | 1.95 | 4.97 |
Ctsd: cathepsin D | 13033 | 1.86 | 2.43 |
Timp2: tissue inhibitor of metalloproteinase 2 | 21858 | 1.85 | 3.94 |
Man2b1: mannosidase 2, alpha B1 | 17159 | 1.71 | 1.51 |
Hexb: hexosaminidase B | 15212 | 1.62 | 2.58 |
Ctsb: cathepsin B | 13030 | 1.54 | 4.06 |
Genes marked in bold code for secretory lysosomal proteins.