Table 5. Blood cell parameters and hematological analyses in Npc1^−/− mice.

	Normal Range	Npc1+/−	Npc1−/−
Leukocytes
WBC (K/µl)	1.8–10.7	8.3±0.80	8.43±1.39
NE (K/µl)	0.1–2.4	1.18±0.16	1.53±0.54
LY (K/µl)	0.9–9.3	6.82±0.67	6.515±0.93
MO (K/µl)	0.0–0.4	0.29±0.03	0.36±0.08
EO (K/µl)	0.0–0.2	0.01	0.025
BA (K/µl)	0.0–0.2	0	0.005
Erythrocytes
RBC (M/µl)	6.36–9.42	9.69±0.05	10.005±0.04
Hb (g/dl)	11.0–15.1	12.85±0.05	11.9±0.30
HCT (%)	35.1–45.4	61.35±0.15	55.3±0.3
MCV (fl)	45.4–60.3	63.3±0.20	55.25±0.05
MCH (pg)	14.1–19.3	13.25±0.15	11.85±0.25
MCHC (g/dl)	30.2–34.2	20.95±0.15	21.5±0.4
RDW(%)	12.4–27.0	15.45±0.05	17.25±0.75
Thrombocytes
PLT (K/µl)	592–2972	855±6	1023.5±55.5
MPV (fl)	5.0–20.0	4.6	4.85±0.05

Blood (∼20µl) was collected from female Npc1^+/− (n = 2, age 63 and 66 days) and Npc1^−/− mice (n = 2, age 63 and 66 days) by cheek bleed. Blood cell parameters were analyzed by Hemavet 950. Values represent mean±SEM. Abbreviations are, WBC = White Blood Cells, NE = Neutrophils, LY = Lymphocytes, MO = Monocytes, EO = Eosinophils, BA = Basophils, RBC = Red Blood Cells, Hb =  Hemoglobin, HCT = Hematocrit, MCV = Mean Corpuscular Volume, MCH = Mean Corpuscular Hemoglobin, MCHC =  Mean Corpuscular Hemoglobin Concentration, RDW = Red Cell Distribution width, PLT  =  Platelet, and MPV = Mean Platelet Volume. K/µl stands for 1000/µl.