Figure 3.

A dendrogram representation of the BACE Bayes factors from the simple model in Fig. 1 captures the hierarchical nature of the underlying landscape. The states are numbered from 0 to 8 on the x axis. The brackets connect states that are being merged and the y-values of the crossbars of these brackets are the BACE Bayes factors between the states being merged. This representation highlights that the three kinetically similar microstates within each macrostate are merged together first (small Bayes factors). Subsequent merger of the more kinetically dissimilar macrostates has a much greater cost (larger Bayes factors).