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Comparison of BDflex and “exact” results for the gating binding-site model. Curves represent the “exact” results and symbols represent the BDflex results. Results for two values of the distance, L1, between the binding site and the dividing surface are shown. kE = 4Da and κ0 = ∞. For induced switch, ω+/ω− = 0.01, ωI+/ωI− = 10, ωI− = ω−, and Vi = 0. Correspondingly, e−βVeff = 11/1.01. For indifferent switch, ω+/ω− = 0.01 and V1 = Veff.
