. 2012 Nov;343(2):401–412. doi: 10.1124/jpet.112.197038

TABLE 2.

The effect of VitD supplementation on bone loss associated with chronic EtOH consumption

After 40 days of chronic EtOH consumption, tibial bone was analyzed by μCT as described under Materials and Methods. Values are mean ± S.E.M. Statistical differences between treatment groups were determined by two-way ANOVA followed by Student-Newman Keuls post hoc analysis. Values with different letter superscripts are significantly different from each other (P < 0.05).

	PF	EtOH	PF/VitD	EtOH/VitD
μCT Trabecular bone parameters
BV/TV, %	6.640 (0.004)^a	4.770 (0.003)^b	4.550 (0.004)^b	4.770 (0.003)^b
Tb.N, 1/mm	2.826 (0.168)^a	2.352 (0.098)^b	2.133 (0.194)^b	2.260 (0.146)^b
Tb.Sp, mm	0.366 (0.035)^a	0.413 (0.027)^a	0.487 (0.035)^b	0.459 (0.027)^a,b
Tb. Th, mm	0.044 (0.001)^a	0.041 (0.001)^b	0.044 (0.001)^a,b	0.042 (0.001)^a,b
μCT Cortical bone parameters
Tt.Ar, mm²	0.153 (0.007)^a	0.138 (0.005)^a	0.141 (0.007)^a	0.134 (0.005)^a
Total diameter, mm	0.035 (0.002)^a	0.026 (0.001)^b	0.035 (0.002)^a	0.031 (0.001)^a,b
Ct.Th, mm	0.173 (0.006)^a	0.149 (0.005)^b	0.179 (0.006)^a	0.165 (0.005)^a,b
Me.Ar, mm²	0.104 (0.006)^a	0.126 (0.006)^b	0.094 (0.006)^a	0.100 (0.005)^a
Ps.Pm, mm	1.442 (0.070)^a	1.529 (0.060)^a	1.367 (0.070)^a	1.375 (0.060)^a
Ec.Pm, mm	0.567 (0.042)^a	0.647 (0.034)^a	0.533 (0.042)^a	0.563 (0.034)^a

Tb.Th, trabecular bone trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular spacing; Tt.Ar, total cross-sectional area; Ct.Th, cortical thickness; Me.Ar, medullary area; Ps.Pm, periosteal perimeter; Ec.Pm, endocortical perimeter.