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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Nat Immunol. 2012 Oct 7;13(11):1110–1117. doi: 10.1038/ni.2427

Figure 3. IL-17-induced pulmonary inflammation is enhanced in the absence of USP25.

Figure 3

(a) Lung infiltrated total cells or neutrophils (Gr1+CD11b+) in bronchoalveolar lavage fluid (BALF) of wild-type and Usp25-/- mice (n=5) injected intranasally with PBS (50 μl) or IL-17 (1 μg in 50 μl PBS) 24 h after injection. ND, Not detected. (b) Histological comparison of lung tissues from mice treated as in (a). Lung sections were stained with hematoxylin and eosin. Original magnification, ×10; Scale bars, 500 μm. (c) ELISA analysis of CXCL1, IL-6 and TNF levels in BALF isolated from mice treated as in (a). Data shown are a representative of two independent experiments. Graphs show mean ± SD, n = 3. *p<0.05; **p<0.01; ***p<0.001.