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. Author manuscript; available in PMC: 2012 Oct 20.
Published in final edited form as: Annu Rev Pharmacol Toxicol. 2011 Sep 27;52:321–336. doi: 10.1146/annurev-pharmtox-010611-134625

Figure 4.

Figure 4

(a) Areas of the brain where metabolism differed when cocaine abusers were exposed to the cocaine-cues video with a directive to purposefully inhibit craving versus when they were exposed to the cocaine-cues video with no inhibition. Metabolism was significantly lower in the right NAc and in the right orbitofrontal cortex with inhibition than it was without inhibition (statistical parametric mapping results p < 0.005 not corrected, cluster > 100 voxels). (b) Regression slope for the differences in metabolism (inhibition versus no inhibition) in the right NAc and in the right BA 44 (r = −0.55, p < 0.006).