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. 1982 Oct;38(1):396–398. doi: 10.1128/iai.38.1.396-398.1982

Retrovirus antigens in brains of mice with scrapie- and murine leukemia virus-induced spongiform encephalopathy.

P M Hoffman, O M Pitts, R G Rohwer, D C Gajdusek, S K Ruscetti
PMCID: PMC347747  PMID: 6292099

Abstract

Wild mouse ecotropic virus-induced spongiform encephalomyelopathy pathologically similar to scrapie was associated with the expression of retrovirus antigens in mouse brains. However, scrapie-infected mice with spongiform encephalopathy showed no increased expression of retrovirus antigens in brain. Thus, the pathogenesis of the scrapie spongiform lesion does not appear to involve activation of endogenous retrovirus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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