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Receiver operating characteristic curves for (left) the catecholamines dopamine (DA), norepinephrine (NE), and epinephrine (EPI) and (right) DA:NE and dihydroxyphenylacetic acid:dihydroxyphenylglycol (DOPAC:DHPG) ratios in newborns at risk for Menkes disease. Note high sensitivity and specificity of DA and NE and low sensitivity and specificity of EPI in distinguishing affected from unaffected newborns and sensitivities of 1.0 at 1−specificities of zero for DA:NE and DOPAC:DHPG ratios
