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. 2012 Oct 11;2012:483123. doi: 10.1155/2012/483123

Figure 2.

Figure 2

CRD test results before EA. CRD0: responses to colorectal distension in 4 groups before (baseline) saline or zymosan treatment (F3,16 = 0.542, P > 0.05); CRD1: responses to colorectal distension in 4 groups after intracolonic treatment with saline or zymosan (F3,16 = 2.593, P > 0.05) on day 8; CRD2: responses to colorectal distension in 4 groups after intracolonic treatment with saline or zymosan (F3,16 = 6.021, P = 0.006, in Z + C versus S + A and Z + C versus S + C) on day 10; CRD3: Responses to colon distension in 4 groups after intracolonic treatment with saline or zymosan (F3,16 = 15.24, P < 0.001, in Z + C versus S + A, Z + C versus S + C, Z + A versus S + A, and Z + A versus S + C) on day 12. Colorectal hypersensitivity did not develop in saline-treated mice. Data are expressed as percentage (mean ± SEM) of the VMR to colorectal distension on the day of baseline testing (day 4) for each animal and normalized to the response to 60 mm Hg distension (100%) to generate stimulus-response functions.