Table 2.
The effects of dihydropyridine CCBs on angiotensin II-induced expression of steroidogenic enzymes.
| Dihydropyridine CCB | Type of affecting Ca2+ channels | StAR | CYP11B1 | CYP11B2 |
|---|---|---|---|---|
| Amlodipine | L, T | → | ||
| Azelnidipine | L, T | ↓ | ↓ | ↓ |
| Benidipine | L, T | ↓ | ↓ | |
| Cilnidipine | L, N | → | ↓ | |
| Efonidipine | L, T | ↑ | ↓ | ↓ |
| Nifedipine | L | → | ↓ | ↓ |
| Nitrendipine | L | → | → |