Skip to main content
. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Gastroenterology. 2011 Dec 7;142(3):531–542. doi: 10.1053/j.gastro.2011.11.034

Figure 3.

Figure 3

Induction of gastric tumor development in the antrum in Villin-Cre+;Klf4fl/fl mice. (A) Incidence (A1 & A2) and locations (A3) of gastric tumor formation in Villin-Cre−;Klf4fl/fl (Klf4+/+), Villin-Cre+;Klf4+/fl (Klf4+/−), and Villin-Cre+;Klf4fl/fl (Klf4−/−) mice at the ages of 35 and 50 weeks with or without MNU-based treatment. (B) Gross morphology of visible tumors (white arrows) in the gastric antrum (B1), corpus (B2), or both (“mixed,” B3) in 50-week-old Klf4−/− mice. (C) Representative photographs of macroscopic views of the entire gastric mucosa in 50-week-old Klf4+/+ (C1) and Klf4−/− (C2) mice and a microscopic view of an antral tumor in the Klf4−/− mouse (C3).

HHS Vulnerability Disclosure