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. Author manuscript; available in PMC: 2012 Oct 22.
Published in final edited form as: Virus Res. 2010 Nov 18;155(1):376–380. doi: 10.1016/j.virusres.2010.11.003

Figure 2. PAK1, but not PAK2, is involved to some extent in the ability of US3 to protect PRV-infected cells from apoptotic cell death.

Figure 2

A. MEF, PAK1−/− MEF and PAK2−/− MEF at 24hpi with wtPRV or US3null PRV, stained for active caspase-3 (green) and nuclei (blue) B. Percentage of active caspase-3 positive MEF, PAK1−/− MEF and PAK2−/− MEF that were either mock infected or infected with wt PRV or US3nullPRV (24 hpi). Three independent replicates of each experiment were performed, data shown are means and standard deviations, and statistical analysis was performed using the SPSS software. Means were compared with an analysis of variance and a least significant difference post hoc test for a multiple comparison of means (α=0.05). Different letters indicate significant differences at the 0.05 level.