Table 1.
Characteristic | Number (%) | ||
---|---|---|---|
IMAGE NEG | IMAGE POS | Significance | |
Total number | 58 | 117 | |
Male | 33 (57%) | 76 (65%) | NS |
Ages (yrs) | |||
Age ZES onset (yrs) | |||
Mean ± SEM | 42.6 ± 1.6 | 41.7 ± 1.1 | NS |
[range] | [14.3-64.9] | [11.0-64.6] | |
Age ZES Diagnosis (yrs) | |||
Mean ± SEM | 48.8 ± 1.4 | 47.8 ± 0.9 | NS |
[range] | [14.2-67.9] | [15.0-69.4] | |
Main Presenting symptoms (%) | |||
Pain | 48(83%) | 101(86%) | NS |
Diarrhea | 46 (79%) | 94 (80%) | NS |
GERD | 32 (55%) | 44 (38%) | NS |
MEN1 present | 0 (0%) | 0 (0%) | NS |
Previous abdominal surgery | 6 (10%) | 51(44%) | <0.0001 |
Acid related surgery | 2 (3.4%) | 25(21%) | 0.0021 |
Hiatal hernia repair | 5 (8.6%) | 1(0.8%) | 0.0081 |
Other | 1 (1.7%) (a) | 27 (23%) (a) | <0.0001 |
Fasting gastrin level (pg/mL) | |||
Mean ± SEM | 1198 ± 449 | 3713 ± 1555 | |
median | 522 | 673 | |
[range] >10-fold increased |
[144-26,000] 9 (15.5%) |
[78-175,300] 40 (34%) |
0.0099 |
Delta Secretin | |||
Mean ± SEM | 4558 ± 2370 | 4590 ± 1188 | NS |
median | 657 | 806 | |
[range] | [88-103,000] | [40-101,650] | |
BAO (mEq/Hr) | |||
Mean ± SEM | 42.8 ± 2.9 (b) | 46.6 ± 2.4(b) | NS |
[range] | [17.9-95] | [11.1-159] |
1 patient in imaging negative group had l nephrectomy for renal cell cancer. In the imaging positive group 3 had a colectomy for colon cancer, 8 had an appendectomy, 5 hysterectomy, 5 cholecystectomy, 2 negative laparotomy for PET, 2 for small bowel obstruction, 1 for renal cell cancer, 1 for small bowel perforation after radiological procedure.
Basal acid output data are shown for patients without previous acid related surgical procedures and include data from 49 patients in imaging negative and 95 patients in imaging positive groups.