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. Author manuscript; available in PMC: 2013 Sep 7.
Published in final edited form as: Mol Neurobiol. 2012 Sep 7;46(1):221–226. doi: 10.1007/s12035-012-8322-5

Figure 1. Endogenous NPD1 biosynthesis is enhanced upon expression of Ataxin-1 82Q in RPE cells.

Figure 1

Primary human RPE cells were transfected with 82Q. Cells (black bars), NPD1 content in media (white bars) and total (grey bars) was measured by LC MS-MS with or without the addition of DHA. * p<0.005. (Figured modified and published with permission from Journal of Biological Chemistry (2012) 287(28):23726-39 “Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1”; Calandria JM, et al.)