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. Author manuscript; available in PMC: 2013 Sep 7.
Published in final edited form as: Mol Neurobiol. 2012 Sep 7;46(1):221–226. doi: 10.1007/s12035-012-8322-5

Figure 2. NPD1 prevents huntingtin-17Q-induced apoptosis in ARPE-19 cells.

Figure 2

ARPE-19 cells transfected with an expression construct containing ht-72Q were treated with 50 nM NPD1, or DHA (100 nM) along with PEDF (10 ng/mL). Apoptosis percentage was calculated by dividing pyknotic over the total count of cells. Results are averages ± SD. * p< 0.0005. (Figured modified and published with permission from Journal of Biological Chemistry (2012) 287(28):23726-39 “Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1”; Calandria JM, et al.)