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. 2012 Oct 13;9(8):715–724. doi: 10.7150/ijms.4815

Table 4.

The genotypes of rs5888 SNP and serum lipid levels in the Han population.

Genotype n TC
(mmol/L)		 TG
(mmol/L)		 HDL-C
(mmol/L)		 LDL-C
(mmol/L)		 ApoAI
(g/L)		 ApoB
(g/L)		 ApoAI/
ApoB
Han Chinese
CC 445 4.99±1.12 1.02 (0.98) 1.74±0.46a 2.86±0.84 1.36±0.28b 0.85±0.19 1.67±0.50
CT 302 4.97±0.92 1.10 (0.86) 1.77±0.64a 2.88±0.87 1.35±0.26b 0.86±0.21 1.68±0.57
TT 60 4.93±1.08 1.09 (0.95) 1.59±0.34 2.84±0.77 1.25±0.18 0.85±0.19 1.52±0.36
F - 0.086 1.722 3.141 0.067 4.780 0.541 2.715
P - 0.918 0.423 0.044 0.935 0.009 0.582 0.067
CC 445 4.99±1.12 1.02 (0.98) 1.74±0.46 2.86±0.84 1.36±0.28 0.85±0.19 1.67±0.50
CT/TT 362 4.96±0.95 1.10(0.86) 1.74±0.60 2.87±0.86 1.34±0.25 0.86±0.21 1.65±0.54
F - 0.099 -1.212 0.010 0.038 1.304 0.865 0.400
P - 0.753 0.225 0.918 0.845 0.254 0.353 0.527
Male
CC 193 5.09±1.15 1.14 (1.04) a 1.75±0.51b 2.84±0.78 1.41±0.33 b 0.88±0.19 1.66±0.48 b
CT 140 5.09±0.97 1.16 (1.08) a 1.66±0.35a 2.99±0.92 1.35±0.29 a 0.93±0.22 1.55±0.56 a
TT 22 5.34±1.09 1.68 (2.61) 1.46±0.31 2.94±0.75 1.22±0.18 0.94±0.20 1.34±0.37
F - 0.623 7.939 5.306 1.228 4.946 2.668 5.459
P - 0.537 0.019 0.005 0.294 0.008 0.071 0.005
CC 193 5.09±1.15 1.14 (1.04) 1.75±0.51 2.84±0.78 1.41±0.33 0.88±0.19 1.66±0.48
CT/TT 162 5.12±0.99 1.30(1.14) 1.64±0.35 2.98±0.90 1.34±0.28 0.93±0.22 1.53±0.54
F - 0.105 -1.863 6.110 2.395 5.376 5.305 7.213
P - 0.746 0.062 0.014 0.123 0.021 0.022 0.008
Female
CC 252 4.90±1.08 0.97 (0.86) 1.75±0.42 2.86±0.89 1.32±0.23 0.82±0.19 1.69±0.51
CT 162 4.89±0.87 1.04 (0.74) 1.85±0.80 2.81±0.82 1.35±0.24 0.81±0.18 1.77±0.55
TT 38 4.72±1.02 1.00 (0.75) 1.66±0.35 2.82±0.79 1.26±0.19 0.79±0.16 1.63±0.32
F - 0.610 0.311 2.212 0.213 2.454 0.669 1.683
P - 0.544 0.856 0.111 0.808 0.087 0.513 0.187
CC 252 4.90±1.08 0.97 (0.86) 1.75±0.42 2.86±0.89 1.32±0.23 0.82±0.19 1.69±0.51
CT/TT 200 4.85±0.90 1.03(0.73) 1.82±0.74 2.81±0.81 1.33±0.23 0.81±0.18 1.74±0.52
F - 0.228 -0.064 1.502 0.421 0.277 0.741 1.060
P - 0.634 0.949 0.221 0.517 0.599 0.390 0.304

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B

a P < 0.05, b P < 0.01 in comparison with the TT genotype of the same ethnic group