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. 2011 Aug 1;1(1):65–75.

Table 1.

Uptake of 64Cu-DOTA-GU40C4 and 64Cu-DOTA-Pctrl in major organs of interest determined by quantitative PET imaging analysis.

64Cu-DOTA-GU40C4 64Cu-DOTA-Pctrl

1 h 4 h 20 h 1 h 4 h 20 h
Tumor * 2.25 ± 0.24 2.15 ± 0.34 * §1.90 ± 0.18 0.34 ± 0.12 0.30 ± 0.14 0.51 ± 0.19
Salivary glands 3.17 ± 0.25 3.00 ± 0.36 §1.83 ± 0.21 0.28 ± 0.08 0.22 ± 0.04 0.42 ± 0.10
Heart 1.30 ± 0.27 1.50 ± 0.20 1.30 ± 0.26 0.31 ± 0.11 0.32 ± 0.05 0.65 ± 0.04
Lung 2.03 ± 0.32 1.77 ± 0.31 1.33 ± 0.06 0.32 ± 0.11 0.42 ± 0.13 0.52 ± 0.01
Liver 24.03 ± 0.90 24.40 ± 0.78 18.53 ± 1.31 13.57 ± 1.38 12.27 ± 1.67 11.63 ± 1.56
Kidney 6.57 ± 1.34 6.50 ± 1.23 5.07 ± 0.91 43.47 ± 4.35 41.53 ± 3.07 30.43 ± 5.66
Muscle 0.49 ± 0.07 0.37 ± 0.06 0.26 ± 0.02 0.14 ± 0.03 0.12 ± 0.04 0.12 ± 0.03

Data are presented as %ID/g ±standard deviation (n = 3).

*

p = 0.06;

p = 0.004;

p = 0.02;

§

p = 0.65.