Figure 2. Simulated AP profiles and current traces under WT (continuous line), and MT conditions where simulated data for ϕ= 0.1 (dashed line), ϕ= 0.25 (dotted line) and ϕ= 1 (grey line) are shown in panels A–F.

A, AP profiles. B, I_Ks profiles during APs. C, I_Kr profiles during APs. D, I_to profiles during APs. E, I_K1 profiles during APs. F, I_CaL profiles during APs. G, changes in APD as the modelling parameter ϕ is increased from 0 (WT) to 1 (MT) condition.