Table 1.
Clinical, diagnostic, and radiologic data from studies about aPL-related chorea.
| Reference | Number of patient (M/F) | Mean age at onset (range) | Isolated aPL positivity*; APS | Unilateral; bilateral chorea at onset | Recidivant forms | Ischemic signs of basal ganglia at CT or MR scan |
|---|---|---|---|---|---|---|
| Cervera et al. (1997) | 50 (2/48) | 21.2 (6–77) | 0; 50 (15 PAPS – 35 SAPS) | 18; 21 (11 NR) | 16/50 | 5/31 |
| Orzechowski et al. (2008) | 18 (6/12) | 44® | 14; 4 | 6; 12 | 6/18 | 1/18 |
| Reiner et al. (2011) | 32 (4/28) | 20.6 (9–62) | 20; 12 (1 PAPS – 11 SAPS) | 15; 15 (2 NR) | 8/32 | 3/31 |
* Also in the context of an immunological disease.
®Median age in 10 non-SLE female patients.
PAPS-SAPS, primary-secondary antiphospholipid syndrome; NR, non-reported.