. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: Neurotoxicology. 2012 Sep 2;33(5):1322–1329. doi: 10.1016/j.neuro.2012.08.008

Table 1.

Average Brain Volumes (mm³) from Ex Vivo MRI of Rats Exposed to Propylthiouracil (PTU)

P25	Control	3 ppm PTU	10 ppm PTU
WM	89.25 ± 11.11^a	101.66 ± 10.23^a	54.18 ± 9.63^b
GM	798.94 ± 38.83^a	831.61 ± 21.00^a	740.3 ± 34.80^b
Total	888.19 ± 46.06^a	933.28 ± 21.39^a	794.48 ± 36.44^b
Hippocampus	66.85 ± 5.20^ab	70.99 ± 2.18^a	61.85 ± 4.65^b
%WM	10.03 ± 0.98^a	10.89 ± 1.06^a	6.82 ± 1.16^b
%Hippocampus	7.52 ± 0.31^a	7.61 ± 0.08^a	7.78 ± 0.44^a

P90	Control	3 ppm PTU	10 ppm PTU
WM	183.37 ± 14.61^a	178.87 ± 9.50^a	139.23 ± 10.79^b
GM	978.35 ± 22.98^a	1018.1 ± 17.07^a	868.29 ± 41.73^b
Total	1161.72 ± 32.83^a	1196.97 ± 12.28^a	1007.52 ± 46.58^b
Hippocampus	90.86 ± 4.13^a	93.2 ± 2.83^a	79.84 ± 5.18^b
%WM	15.77 ± 0.95^a	14.95 ± 0.85^ab	13.82 ± 0.90^b
%Hippocampus	7.82 ± 0.19^a	7.79 ± 0.23^a	7.92 ± 0.35^a

WM = White Matter; GM = Gray Matter; Total = Total Segmented Volume; %WM = Percent White Matter; % Hippocampus = Percent Hippocampus. Values that share the same letter are not significantly different from each other (i.e., P > 0.05)