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. Author manuscript; available in PMC: 2013 Aug 31.
Published in final edited form as: Cell. 2012 Aug 31;150(5):1068–1081. doi: 10.1016/j.cell.2012.08.011

Figure 3. Global validations of the map of high confidence human protein complexes.

Figure 3

A- Complex size distribution of the 622 inferred complexes. B- Network of predicted human protein complexes proportioned according to subunit number and displaying existing curations, validation status by AP/MS (Malovannaya et al., 2011), and PPI connectivity (proportioned edge width). C- Proportions of annotated complexes in public repositories (CORUM, PINdb, REACTOME, HPRD) or independently experimentally-verified. D- Enrichment analysis showing overlap with large-scale APMS datasets generated for human (Hutchins et al., 2010; Malovannaya et al., 2011) and (via orthology) fly (Guruharsha et al., 2011). See also Table S3.